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The Panel feels strongly that all physicians treating patients with prostate cancer have the responsibility to inform patients of the availability of clinical trials for the management of this disease.
Fatigue and hypertension were the most common clinically relevant adverse events associated with enzalutamide treatment.
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Some people want to use laetrile if they are told that their cancer can't be cured with conventional cancer treatments.
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Objective: To evaluate the efficacy of bicalutamide vs cyproterone acetate in preventing PSA flare (as a surrogate for tumour flare) for patients requiring luteinizing hormone-releasing hormone (LHRH) analogue therapy for prostate cancer.
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These adverse effects are manageable in most patients but, as prostate cancer is now being diagnosed at an earlier stage and in younger men than ever before, there is an emphasis on the need for treatment options that enable patients to maintain quality of life.
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Blood samples for the determination of plasma bicalutamide concentrations were obtained at regular intervals over 672 hours after dose administration.
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Furthermore, the lack of an expected "dose-response" relationship between the amount of breast tissue removed and the magnitude of symptomatic relief in these studies raises questions about the validity of these studies and the effectiveness of breast reduction as a method of relieving shoulder and back pain.
Between March 22, 2011, and July 11, 2013, 375 patients were randomly assigned, 184 to enzalutamide and 191 to bicalutamide.
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Treatment with bicalutamide should be started at the same time as treatment with an LHRH analog.
One study has evaluated the efficacy of a neoadjuvant regimen without an LHRH agonist, comprised of Dutasteride and Bicalutamide to reduce prostate volume.
withdrawal of bicalutamide and initiation of steroid therapy resulted in clinical improvement
This plan often works well for patients whose prostate cancer may take eight to 10 years to progress and would avoid the complications of therapy.
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